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A type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival.
The Bcl-2 family of proteins are key regulators of programmedcelldeath.
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Apoptosis, or programmedcelldeath, is a highly conserved cellular suicide mechanism.
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More than 10 different types of programmedcelldeath forms have been discovered.
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The oncogenic protein Bcl-2 functions as a potent inhibitor of programmedcelldeath.
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These genes define a genetic pathway for programmedcelldeath in C. elegans.
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After acute GATA-3 loss, adult mice exhibited undifferentiated luminal cell expansion with basement-membrane detachment, which led to caspase-mediatedcelldeath in the long term.
Usage of apoptosis in English
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However, other events occur prior to the initiation of apoptosis in cells.
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However, the molecular mechanisms of cell apoptosis after SDT treatment remain unclear.
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Conclusion: Energy metabolism plays an important role in hepatocyte apoptosis during ALF.
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However, the role of p300 in protection against doxorubicin-induced apoptosis is unknown.
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However, the mechanism of mitochondria-mediated apoptosis in aged hearts remains poorly understood.
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Seven days later, the rates of migration, differentiation and apoptosis were evaluated.
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The treatment, however, did not affect proliferation and apoptosis of salvaged cardiomyocytes.
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Western blotting was used to examine the changes in apoptosis-associated protein Bcl-2.
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It is now possible to systematically determine how individual cancers escape apoptosis.
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In addition, SSBE treatment also increased cellular apoptosis in a mitochondrial-dependent manner.
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In particular, caspase-3 plays a key role in the execution of apoptosis.
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Conclusion: Hepatocyte apoptosis plays an important role in the pathogenesis of AHF.
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Recent studies have shown that increased lymphocyte apoptosis contributes to sepsis-induced mortality.
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Preliminary evidence of selective apoptosis of tumor under these conditions is presented.
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Oxidative stress and apoptosis play a vital role in the aging process.
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Moreover, PKCε inhibits mitochondrial apoptosis and is associated with the Bcl family.